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Partnering with Oncolys BioPharma

We are seeking collaboration opportunities with companies, research institutions, and researchers that have innovative technologies capable of enhancing the value of our products, ensuring stable supply, and supporting the future development of our oncolytic adenovirus products, including Telomelysin (OBP-301). We welcome proposals in the following areas:

  1. Technologies for the Intratumoral Administration of Oncolytic Adenoviruses
    Technologies that enable more accurate and safer intratumoral administration using various endoscopic systems, including prefilled syringes, dedicated injection needles, and devices that allow precise control of injection volume and pressure, as well as technologies that improve the distribution of oncolytic adenoviruses within tumors.
    We also welcome technologies for uniform delivery to multiple sites administration of superficial tumors, including the injection devices with multiple needles, microneedles, and multi-pin array devices.
  2. Formulation and Storage Technologies
    Technologies that improve the stability of oncolytic adenovirus formulations and formulation technologies that enable storage under refrigerated conditions rather than frozen storage.
  3. Manufacturing and Purification Technologies
    Technologies that improve the productivity of oncolytic adenoviruses manufacturing through high productivity cell lines and optimized cell culture processes, technologies that enhance recovery and purity during downstream purification, and filtration or membrane separation technologies that minimize viral adsorption and product loss.
  4. Biomarker Technologies and Research for Oncolytic Adenoviruses
    Technologies for analyzing and visualizing local and systemic antitumor immune responses induced by oncolytic adenovirus therapy, as well as research aimed at elucidating its mechanism of action, identifying predictive biomarkers of therapeutic efficacy, and exploring potential combination therapies.
Technology Area Technologies we are seeking Examples of Relevant Technologies, Devices, and Research Topics
1. Technologies for Intratumoral Administration Technologies that enable precise and safe intratumoral administration of oncolytic adenoviruses using various types of endoscopes, as well as technologies that improve their distribution within tumors.
  • Technologies for administration under endoscopic guidance
  • Prefilled syringes
  • Specialized injection needles
  • Devices for controlling injection volume and pressure
  • Technologies that improve distribution within tumors
  • Needles for administration at multiple sites
  • Microneedles for intratumoral administration
  • Needle array devices for intratumoral administration, etc.
2. Formulation & Storage Technologies Technologies for stabilizing oncolytic adenovirus formulations and enabling refrigerated storage.
  • Technologies for stabilizing viral formulations
  • Formulation technologies that enable refrigerated storage, etc.
3. Manufacturing & Purification Technologies Technologies that improve productivity, recovery rates, and purity in processes used to manufacture and purify oncolytic adenoviruses.
  • Cell lines capable of producing high viral yields
  • Cell culture technologies
  • Purification technologies
  • Filtration and membrane separation technologies
  • Technologies that reduce the adsorption and loss of viral particles, etc.
4. Research on Biomarkers and Mechanisms of Action Research on anti-tumor immune responses induced by oncolytic adenoviruses, including biomarker discovery for efficacy prediction and combination therapy strategies.
  • Analysis and visualization of local and systemic immune responses
  • Studies of mechanisms of action
  • Research on biomarkers for predicting treatment response
  • Research on combination therapies, etc.

Beyond the areas listed above, we welcome proposals for various technologies that could further enhance the value of our oncolytic adenovirus technology.

If you are interested in collaborating with us, please submit your proposal using the inquiry form below.

Inquiry Form

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